The Best Ergonomic Mice 2025

1. Logitech - MX Master 2S Bluetooth Wireless Mouse with Hyper-Fast Scrolling - Graphite

108 keys; 2-shot PBT keycaps; USB Interface; Cherry MX red switch; Blue LED backlight

The ultimate precision mouse for power users. Harness the power of Logitech Flow and seamlessly move content between three computers. Scroll through documents and web pages faster and easier with the speed-adaptive scroll wheel. Powers up for an entire day in just three minutes. A sculpted, hand-crafted shape ensures comfortable hand and wrist support.

2. Turtle Beach - Pure SEL Ultra-Light Wired Ergonomic RGB Gaming Mouse with 8K DPI Optical Sensor & Mechanical Switches - Black

The Turtle Beach Pure SEL Gaming Mouse leverages over a decade of Kone’s ergonomic engineering into a 49g ultra lightweight design allowing for quick flick shots and large mouse swipes helping you hit your targets faster than ever. Enjoy crisp tactile performance with mechanical switches that are rated for 20 million click durability, precisely pre-tensioned with leaf-springs improving reliability and response time to deliver the most accurate satisfying click ever. The PixArt 8K DPI sensor provides precise tracking and 200 IPS tracking speed in combination with the pure PTFE glides giving you the fastest and smoothest experience possible. Pure SEL is designed to shine with a stylish semi-translucent shell with a fully customizable RGB projection of the Turtle Beach logo onto the back of the mouse and AIMO intelligent lighting compatibility.

3. Turtle Beach - Pure Air Ultra-Light Wireless Ergonomic RGB Gaming Mouse with 26K DPI Optical Sensor & 125 hour Battery - Black

The Turtle Beach Pure Air Wireless Gaming Mouse leverages over a decade of Pure’s ergonomic engineering into a 54g ultra lightweight design allowing for quick flick shots and large mouse swipes without sacrificing durability, helping you hit your targets faster than ever. Untether your mouse and taking advantage of the dual wireless system allowing you to seamlessly switch between gaming grade 2.4GHz wireless and Bluetooth. Enjoy endless nights of gaming with up to 125 hours of continuous battery life and rapid charging where 10 minutes of charge provides 5 hours of game time. Faster than any mechanical switch, the TITAN Optical switch with adjustable debounce provides a long-lasting 100 million click life cycle, and speed-of-light actuation while the 26K Owl-Eye Optical sensor gives you game winning speed and accuracy. Left and right click buttons are precisely pre-tensioned improving response time and delivering the most accurate satisfying click ever. The Pure PTFE glides and PhantomFlex charging cable further amplify unrestricted gameplay, giving you the fastest, smoothest, and most precise experience possible. Pure Air is designed to shine with a stylish semi-translucent shell and a fully customizable AIMO intelligent RGB projection of the Turtle Beach logo onto the back of the mouse.

4. Contour - Unimouse Wireless Ergonomic Mouse

Unimouse is designed with your comfort in focus. The ergonomic shape reduces the strain on your hands and wrists, allowing you to work without discomfort. With the patented articulated hinge, you can adjust the angle of the Unimouse to any position from 35 to 70 degrees. The friction-based locking system is easy to use and stable in any position. It features 6 programmable buttons that can be set to virtually all functions, meeting your unique needs. The adjustable thumb support can be adjusted in all directions, in/out, up/down, forward/backward, tilt and rotation. This reduces grip pain and pressure on the base joint of the thumb, thereby reducing strain injuries, and you can hold the mouse relaxed - no matter the size or shape of your hand. Unimouse boasts a dynamic, adjustable thumb support that gives you near infinite adjustability. With 3 distinct points of adjustment the Unimouse allows you to choose the perfect place for the thumb support. Your natural posture is your body at rest. The articulating thumb support encourages users to move the length, width, and angle to find the perfect spot to let your thumb rest and eliminate harmful gripping. This allows you full control while reducing tension in your hands and forearms. Finding the right fit Whether you're comfortable at 35°, 70°, or anywhere in between, the adjustable hinge on the Unimouse allows you to achieve the maximum comfort and ergonomic benefits from your Unimouse in finding a position that allows your hand to work in its natural posture. The Unimouse is available in both right-hand and left-hand version

The Unimouse Wireless from Contour Design is designed to encourage regular changing of hand position throughout the day or as discomfort is detected. It incorporates a 35° - 70° friction-based tilt mechanism and a fully articulating thumb support designed to adapt the mouse to fit the dimensions of most hands. The Unimouse Wireless is available in models for both the right and left hands.

5. Logitech - M525 Wireless Optical Ambidextrous Mouse - Black

Advanced optical technology; contoured design with 3 buttons; soft rubber grips; smart sleep mode; unifying receiver connects up to 6 compatible devices

Logitech M525 Wireless Mouse: Everyone in your household can comfortably navigate features on your PC or Mac with this mouse, which features an ambidextrous, contoured shape with rubber grips for right- and left-handed use. The included unifying receiver allows you to wirelessly connect the mouse and up to 5 other devices to your computer, so you can enjoy freedom of motion.

6. Logitech - ERGO M575 S Wireless Ergonomic Trackball Mouse - Wireless - Black

Minimize movement and maximize comfort with the Logitech ERGO M575S wireless trackball mouse. Thumb control lets you move the cursor without moving your arm, while the sculpted ergonomic design fully supports your hand and keeps your forearm in a more natural position. This wireless ergonomic mouse has been developed by Logi Ergo Lab experts, user-tested and certified by ergonomists to give you 25% less muscle strain in your forearm . The smooth and responsive thumb control can be used anywhere – and since it doesn’t need to be moved, the ERGO M575S is perfect for tight setups and busy desks.

7. Logitech - ERGO M575 S Wireless Ergonomic Trackball Mouse - Wireless - White

Minimize movement and maximize comfort with the Logitech ERGO M575S wireless trackball mouse. Thumb control lets you move the cursor without moving your arm, while the sculpted ergonomic design fully supports your hand and keeps your forearm in a more natural position. This wireless ergonomic mouse has been developed by Logi Ergo Lab experts, user-tested and certified by ergonomists to give you 25% less muscle strain in your forearm . The smooth and responsive thumb control can be used anywhere – and since it doesn’t need to be moved, the ERGO M575S is perfect for tight setups and busy desks.

8. Logitech - MX ERGO S PLUS Wireless Ergonomic Trackball Mouse with 6 Programmable Buttons - Wireless - Graphite

The MX Ergo S Plus is Logitech’s most advanced ergonomic trackball mouse yet, with a 20-degree tilt angle and a 10-degree detachable wedge, and precise thumb control - user-tested and certified by United States Ergonomics. The MX Ergo S wireless ergonomic mouse is sculpted to fit the palm of your hand while keeping it relaxed, and it tilts 20 to 30 degrees for 27% less muscle activity in the forearm, providing elevated comfort throughout your day. Work faster with 6 customizable buttons and a DPI button to effortlessly switch between speed and high-precision tracking. Now with 80% quieter clicks. For even more control that's tailored to your needs, assign time-saving shortcuts and Smart Actions using the Logi Options+ App. Connect your wireless mouse to 2 devices via Bluetooth or the included Logi Bolt receiver and switch between devices with a click of the Easy-Switch button.

9. HP - X3000 G2 Wireless Optical Ambidextrous Mouse - Black

Compatible with HP d5460, ps pro68550, psc6380, and psc6760 printers; dries instantly and resist smudges; dark black

An ambidextrous travel-sized wireless mouse with long battery life. Improve the way you connect and communicate, work and play. Built with strict HP standards and guidelines, this world-class HP Wireless Mouse X3000 G2 effortlessly blends sleek, modern design with life-enhancing, advanced features.

10. Kensington - Orbit 72337 Optical Gaming Ambidextrous Mouse with Scroll Ring - Black and Blue

Orbit 72337 Trackball with Scroll Ring

All-day comfort and scrolling come together in the Kensington Orbit Trackball with Scroll Ring. The scroll ring allows you to fly through web pages and documents. And all while delivering comfort and space savings no mouse can match.