The Best Mood & Stress Support Supplements 2025

Updated On April 15th, 2025

Looking for the best Mood & Stress Support Supplements? You aren't short of choices in 2022. The difficult bit is deciding the best Mood & Stress Support Supplements for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Mood & Stress Support Supplements.

Rank Product Name Score
1
Inverness Medical Posture D Calcium with Vitamin D & Magnesium, 120 ea

Inverness Medical Posture D Calcium with Vitamin D & Magnesium, 120 ea

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100%
2
SlowMag® Mg Muscle + Heart Magnesium Chloride Supplement Tablets with Calcium 60ct

SlowMag® Mg Muscle + Heart Magnesium Chloride Supplement Tablets with Calcium 60ct

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96%
3
Nature's Bounty Coral Calcium 1000 mg Plus Vitamin D & Magnesium Capsules 120 Capsules

Nature's Bounty Coral Calcium 1000 mg Plus Vitamin D & Magnesium Capsules 120 Capsules

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96%
4
Caltrate 600+D3 Calcium and Vitamin D Supplement Tablets - 120 Count

Caltrate 600+D3 Calcium and Vitamin D Supplement Tablets - 120 Count

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94%
5
Caltrate Bone Health 600+D3 Calcium Tablets, 200 Ct

Caltrate Bone Health 600+D3 Calcium Tablets, 200 Ct

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94%
6
Spring Valley DHEA 50mg Tablets, Dietary Supplement, 50 Count

Spring Valley DHEA 50mg Tablets, Dietary Supplement, 50 Count

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94%
7
Nature Made Magnesium Oxide Tablets, 250 mg, 100 Count

Nature Made Magnesium Oxide Tablets, 250 mg, 100 Count

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92%
8
Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules, 300 mg, 1150 Count

Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules, 300 mg, 1150 Count

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92%
9
Caltrate Bone Health Advanced 600+D3 plus Minerals Calcium Tablets, 165 Ct

Caltrate Bone Health Advanced 600+D3 plus Minerals Calcium Tablets, 165 Ct

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90%
10
DHEA Dietary Supplement Tablets - 50 CT

DHEA Dietary Supplement Tablets - 50 CT

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82%

1. Inverness Medical Posture D Calcium with Vitamin D & Magnesium, 120 ea

Inverness Medical Posture D Calcium with Vitamin D & Magnesium, 120 ea
100%

Our Score

Calcium with Vitamin D & Magnesium, 600 mg, Caplets 120 caplets Dietary Supplement. Contains phosphorus and 4X more vitamin D. Why has vitamin D been increased to 500 IU per caplet? Vitamin D is extremely important in helping your body absorb calcium. Recent studies have shown that vitamin D has other important benefits such as maintaining breast colon and cardiovascular health. Many of us don't get enough sun exposure or eat foods sufficiently rich in vitamin D, so now a daily regimen of Posture-D provides 1000 IU of vitamin D. Why is phosphorus important? According to recent studies, consuming calcium with phosphorus is more effective at building strong bones than consuming calcium alone. If you are among the 50 millions American women who don't obtain the daily RDI for phosphorus from their normal diet. You need Posture-D, the only leading calcium supplement that contains the ratio of calcium to phosphorus found in healthy bones. And, now it has 4x vitamin D. Are you getting all the calcium, phosphorus and extra vitamin D you need? Gluten-free. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) Made in USA of US and imported ingredients. Two caplets daily to provide a daily source of calcium and phosphorus, or as recommended by your physician. Can be taken with your multivitamin. Store in a dry place, 59-86 degrees F (15-30 degrees C). Keep out of reach of children. Pregnant or nursing women and individuals taking any medication, or who have underlying health conditions should consult with their physician before using this product. Tamper-evident seal under cap. Do not use if printed seal is broken or missing. 120 caplets Waltham, MA 02453 888-698-5032 2009 Inverness Medical.

Calcium with Vitamin D & Magnesium, 600 mg, Caplets Dietary Supplement. Contains phosphorus and 4X more vitamin D. Why has vitamin D been increased to 500 IU per caplet? Vitamin D is extremely important in helping your body absorb calcium. Recent studies have shown that vitamin D has other important benefits such as maintaining breast colon and cardiovascular health. Many of us don't get enough sun exposure or eat foods sufficiently rich in vitamin D, so now a daily regimen of Posture-D provides 1000 IU of vitamin D. Why is phosphorus important? According to recent studies, consuming calcium with phosphorus is more effective at building strong bones than consuming calcium alone. If you are among the 50 millions American women who don't obtain the daily RDI for phosphorus from their normal diet. You need Posture-D, the only leading calcium supplement that contains the ratio of calcium to phosphorus found in healthy bones. And, now it has 4x vitamin D. Are you getting all the calcium, phosphorus and extra vitamin D you need? Gluten-free. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) Made in USA of US and imported ingredients.

2. SlowMag® Mg Muscle + Heart Magnesium Chloride Supplement Tablets with Calcium 60ct

SlowMag® Mg Muscle + Heart Magnesium Chloride Supplement Tablets with Calcium 60ct
96%

Our Score

More of the Magnesium You Need SlowMag® Mg Muscle + Heart magnesium chloride dietary supplement is one of the best ways to get the magnesium you need to support: • Proper Muscle Function* • Energy Metabolism* • Cardiovascular Health* Why is it Called SlowMag? SlowMag® Mg Muscle + Heart magnesium chloride + calcium tablets have a special enteric coating that allows them to pass through the gastric juices of the stomach, making them SLOOOOOW to digest. This reduces the chance of an upset stomach caused by some magnesium supplements. And SlowMag® Mg tablets are specially formulated to maximize absorption as well as be easy on the stomach. SlowMag® Mg Muscle + Heart is a Specially Formulated Magnesium Supplement: • Magnesium chloride for increased absorption versus magnesium oxide (1) • Magnesium chloride + calcium for normal nerve and muscle function* • Enteric-coated tablets to help reduce the chance of stomach upset *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. 1. Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnesium Research. 2001;14(4):257-262. 2. USDA Agricultural Research Service. Continuing Survey of Food Intakes by Individuals (CSFII) 1994-96, 1998.

SlowMag® Mg Muscle + Heart Magnesium Chloride Supplement Tablets with Calcium 60ct WHY MAGNESIUM SUPPLEMENTS: 7 out of 10 Americans are below the Dietary Reference Intake for magnesium (2) CARDIOVASCULAR HEALTH: Magnesium helps maintain normal heart rhythms and blood pressure already in the normal range.* MUSCLE FUNCTION: This magnesium chloride + calcium supplement supports proper muscle function*" ENERGY: Magnesium helps maintain electrolyte and energy levels.* MEMORY: Magnesium supports learning and memory performance in aging adults* BONE HEALTH: This magnesium chloride + calcium supplement supports bone health* NERVOUS SYSTEM: Magnesium supports a healthy nervous system* BETTER ABSORPTION. SlowMag is formulated with magnesium chloride for increased absorption versus magnesium oxide (1) THE SLOWMAG MG® FAMILY: Also try SlowMag® Mg Muscle Health + Recovery* Magnesium Gummies and SlowMag Mg® Calm + Sleep* Magnesium Tablets

3. Nature's Bounty Coral Calcium 1000 mg Plus Vitamin D & Magnesium Capsules 120 Capsules

Nature's Bounty Coral Calcium 1000 mg Plus Vitamin D & Magnesium Capsules 120 Capsules
96%

Our Score

The company for all your vitamin and nutritional needs. Active Ingredients: 2 Capsules: Vitamin C (as Ascorbic Acid) 5 mg; Vitamin D3 (as Cholecalciferol) 400 IU; Calcium (from 1000 mg Coral Calcium) 370 mg; Magnesium (as Magnesium Oxide, Magnesium Citrate) 56 mg; Rice Flour; Gelatin; Silica; Vegetable Magnesium Stearate Uses: Modern farming methods and over-processed food often strip our diet of important minerals. Coral Calcium Plus Vitamin D3 with Magnesium and Vitamin C supports bone health.* Vitamin D3 works by contributing to calcium absorption.* Our coral calcium is mined, not collected, from an above ground source - making it environmentally friendly as it prevents damaging coral reefs. No artificial color, flavor or sweetener. No preservatives, sugar, milk, lactose, soy, gluten, wheat, yeast, fish. Sodium free. *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Coral Calcium, 1000 mg, Capsules Mineral Supplement. Plus vitamin D3 & magnesium. Promotes bone health. Earth friendly source. Modern farming methods and over-processed food often strip our diet of important minerals. Coral Calcium plus vitamin D3 with magnesium & vitamin C supports bone health. Vitamin D3 works by contributing to calcium absorption. Our Coral Calcium is mined, not collected, from an above ground source - making it environmentally friendly as it prevents damaging coral reefs. This product contains 185 mg of elemental calcium per capsule counted towards your daily calcium needs. Laboratory tested. No artificial color, flavor or sweetener, no preservatives, no sugar, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.)

4. Caltrate 600+D3 Calcium and Vitamin D Supplement Tablets - 120 Count

Caltrate 600+D3 Calcium and Vitamin D Supplement Tablets - 120 Count
94%

Our Score

Bone Supplement with Concentrated Active Ingredients Caltrate 600+D3 Calcium and Vitamin D Supplement Tablets offer the highest level of vitamin D3 (1) to help maximize calcium absorption and support healthy bones, joints and muscles (2) so you can live life to the fullest. Formulated with calcium carbonate—nature's most concentrated form of calcium—Caltrate contains 600 mg of calcium per tablet. Your body needs calcium for more than just strong bones; it also plays a role in supporting your everyday activities like muscle contractions, blood clotting and nerve function. In addition to calcium, your body needs vitamin D to help calcium work for you. Caltrate calcium with vitamin D supplements contain high levels of vitamin D3 to help maximize calcium absorption and maintain healthy bones. (2) Key Benefits Concentrated calcium supplements with 600 mg of calcium carbonate High levels of vitamin D3 help maintain healthy bones (2) Vitamin and calcium tablets are easy to take Easy to Take Calcium and Vitamin D In addition to 600+D3 Calcium and Vitamin D, Caltrate tablets are also available in 600+D3 plus Minerals. Simply take one to two tablets daily with food or as directed by a physician to get the calcium and vitamin D your body needs to support healthy bones and muscles and keep you moving. (2) (1) Per tablet; among leading calcium supplement brands. (2) These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

120 count bottle of Caltrate 600+D3 600 mg Calcium and Vitamin D Supplement Tablets Caltrate offers the highest level of vitamin D3 per tablet among leading calcium supplement brands (1) Calcium and vitamin D tablets help support strong bones and everyday activities like muscle contractions, blood clotting and nerve function (2) High levels of vitamin D3 in Caltrate calcium and vitamin D3 tablets help maximize calcium absorption (2) Vitamin D and calcium tablets contain 600 mg calcium and 20 mcg of vitamin D3 per tablet Take one to two tablets daily or use as directed by your physician

5. Caltrate Bone Health 600+D3 Calcium Tablets, 200 Ct

Caltrate Bone Health 600+D3 Calcium Tablets, 200 Ct
94%

Our Score

To get the calcium and vitamin D your body needs to support healthy bones and muscles and keep you moving, trust Caltrate, the 1 selling brand of calcium supplements in the United States. Your body needs calcium for more than just strong bones; it also plays a role in supporting your everyday activities like muscle contractions, blood clotting and nerve function. However, you need vitamin D to help calcium work for you. If you have a deficiency in vit. D, it can reduce the amount of calcium your body absorbs and can result in weakened or brittle bones, making it harder to maintain your active, healthy lifestyle. With the advanced levels of vitamin D3 in the Caltrate 600 plus D3 supplements, your body can get the help it needs to maximize calcium absorption and keep you moving throughout life. (1,3) Caltrate contains calcium carbonate, one of the two most common forms of calcium used in dietary supplements. It is the most concentrated form of calcium, so the tablets can be smaller, allowing for easier swallowing, and you may take fewer. With fewer tablets needed in your daily routine, your bottle of Caltrate 600 plus vitamin D3 may last longer compared to other supplement forms, which contain calcium citrate. Backed by over 25 years of nutritional science research, Caltrate is formulated with consideration given to recommendations from the National Academy of Sciences to support bone and overall health. (1) (1) These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. (2) Per tablet; among leading calcium supplement brands. (3) IRI retail sales data supports that Caltrate is the 1 selling calcium supplement brand in the US

Each box contains 200 tablets of Caltrate 600 + D3 to support strong, healthy bones. (1) No other calcium supplement has more vitamin D3 to help maximize calcium absorption. (1,2) Trust Caltrate, the expert in calcium, to help replenish the calcium & help provide the vitamin D3 your body uses every day. (1) Sufficient calcium & vitamin D as part of a healthy diet may reduce the risk of osteoporosis. (1) The calcium in Caltrate 600+D3 also plays an important role in the health of your nerves, hormones and teeth. (1)

6. Spring Valley DHEA 50mg Tablets, Dietary Supplement, 50 Count

Spring Valley DHEA 50mg Tablets, Dietary Supplement, 50 Count
94%

Our Score

Help to support your body's metabolism of sugars with the Spring Valley DHEA Tablets.* DHEA stands for dehydroepiandrosterone, which is a natural hormone that your body produces. With older age, these levels of DHEA can decline. This sugar metabolism support supplement can help bring balance to those levels again. Another key feature of this product is that it is non-GMO, gluten and dairy-free. The Spring Valley supplement is an ideal product for adults more mature in age. The Spring Valley DHEA Tablets can help boost decreased amounts of the body's metabolism sugar levels. Spring Valley understands living a healthy, balanced lifestyle is the key to being your best self. With an affordable range of products inspired by nature, Spring Valley supports your and your family's health and holistic wellbeing. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Spring Valley DHEA Tablets, 50 mg, 50 Count 50-day supply Non-GMO, gluten-free and dairy-free The serving size of the sugar metabolism support pill is: 1 tablet daily Your body naturally produces DHEA, but these natural levels can decline with age Each serving provides 50mg of DHEA in one easy tablet Supports sugar metabolism* United States coin image from United States Mint

7. Nature Made Magnesium Oxide Tablets, 250 mg, 100 Count

Nature Made Magnesium Oxide Tablets, 250 mg, 100 Count
92%

Our Score

Magnesium, 250mg, Tablets, Bottle 100 CT Dietary Supplement. List No. 1269. L200. Helps support nerve, muscle & heart function. Magnesium also supports healthy bones and teeth, and is essential in converting food into cellular energy. Color derived from natural source - No synthetic dyes. No artificial flavors. No preservatives. No yeast or starch. Gluten free. www.NatureMade.com. Magnesium tablets are made to Nature Made's guaranteed purity and potency standards. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) Suggested Use: Take on tablet daily with a meal. For easier swallowing, take with water before and during ingestion. Keep bottle tightly closed. Store in a cool, dry place, out of reach of children. Caution: Consult a physician before use, if you have kidney disease or if you are taking prescription medications. Do not use if imprinted seal under cap is broken or missing. 100 tablets Mission Hills, CA 91346-9606 800-276-2878

Magnesium, 250 mg, Tablets Dietary Supplement. Helps nerve & muscle function - Magnesium is also essential in the formation of bones and teeth and in converting blood sugar into energy. No artificial colors. No artificial flavors. No preservatives. No yeast, starch or gluten. www.NatureMade.com. Magnesium tablets are made to Nature Made's guaranteed purity and potency standards. Enter code for Wellness Rewards Points at www.NatureMade.com (valid only for US and Puerto Rico residents). (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.)

8. Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules, 300 mg, 1150 Count

Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules, 300 mg, 1150 Count
92%

Our Score

Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules are a vegetarian supplement that may support mood health and emotional balance.* These capsules contain no gluten and artificial colors and flavors. The suggested dose is two capsules, three times per day, preferably with a meal. You can rest assured that Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules are produced with strict quality guidelines and are backed by our quality guarantee. Spring Valley understands living a healthy, balanced lifestyle is the key to being your best self. With an affordable range of products inspired by nature, Spring Valley supports your and your family's health and holistic wellbeing.

Spring Valley Standardized Extract St. John's Wort Mood Health Dietary Supplement Vegetarian Capsules, 300 mg, 150 Count Dietary supplement that supports mood health* 300 mg standardized extract St. John's Wort per capsule Contains no gluten and artificial flavors and colors Tamper-evident packaging 90 vegetarian capsules per bottle United States coin image from the United States Mint *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

9. Caltrate Bone Health Advanced 600+D3 plus Minerals Calcium Tablets, 165 Ct

Caltrate Bone Health Advanced 600+D3 plus Minerals Calcium Tablets, 165 Ct
90%

Our Score

If you don't get the calcium you need to support important bodily activities, your body will take the calcium from your bones and this can make them weaker over time. Caltrate 600+D3 Plus Minerals (including magnesium) offers a dual benefit formula that goes beyond calcium for an enhanced bone health formula. In addition to calcium for bone flexibility, key essential minerals like zinc, copper and manganese help support collagen production for flexibility to help you keep moving and doing the things you enjoy. (1,3) To get the most out of your diet or calcium supplements, you need vitamin D to help absorb calcium. Backed by over 25 years of nutritional science research, Caltrate is formulated with consideration given to recommendations from the National Academy of Sciences to support bone and overall health. So, it's no surprise that Caltrate is the 1 selling calcium supplement brand in the United States and trusted by so many people like you. (1,4) Also try Caltrate Plus Minerals chewables and easy-to swallow mini tablets. (1) These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. (2) Per tablet; among leading calcium supplement brands. (3) Refers to Copper, Manganese, and Zinc. (4) IRI retail sales data supports that Caltrate is the 1 selling calcium supplement brand in the US

Includes one, 165 count bottle of Caltrate 600+D3 Plus Minerals calcium supplement tablets to nourish your bones. (1) Dual benefit formula includes calcium and vitamin D3 for bone strength and minerals for flexibility. (1) Includes essential minerals like manganese (3) to help support collagen production for resilient bones. (1) Caltrate Plus Minerals has the most vitamin D3 to help your body maximize calcium absorption. (1,2) Caltrate is the #1 selling brand of calcium supplements in the United States. (4) Also available in delicious chewable tablets and easy-to-swallow mini tablets

10. DHEA Dietary Supplement Tablets - 50 CT

DHEA Dietary Supplement Tablets - 50 CT
82%

Our Score

Maintain a healthy lifestyle with the help of these DHEA Dietary Supplement Tablets. They're formulated to promote healthy hormone levels and encourage greater physical well-being. Take these dietary supplement pills to get support for muscle growth. They can also be used to improve fitness levels. These tablets are ideal for men with an active lifestyle. They help promote a stronger immune system and a healthy body composition for long lasting health. These men's vitality pills have been clinically tested to ensure safety and quality. Each one is made with ingredients from natural sources. These tablets are suitable for regular use each day. They're available in a 50-count container.

DHEA Dietary Supplement Tablets: Clinically tested strength Ideal for men with an active lifestyle Men's vitality pills for maintaining healthy hormone levels Encourages physical well being Supports muscle growth Improves fitness levels Promotes a stronger immune system Helps maintain a healthy body composition Ideal for long lasting health Safe and intended for regular use each day Made with ingredients from natural sources Large multi-count container for long lasting use


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