The Best Specialty Pain Relievers 2025

Updated On April 23rd, 2025

Looking for the best Specialty Pain Relievers? You aren't short of choices in 2022. The difficult bit is deciding the best Specialty Pain Relievers for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Specialty Pain Relievers.

Rank Product Name Score
1
Mentholatum Original Chest Rub Ointment, Jar, 1oz

Mentholatum Original Chest Rub Ointment, Jar, 1oz

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94%
2
Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, 16 ct

Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, 16 ct

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94%
3
Midol Complete Menstrual Pain Relief Caplets w/ Acetaminophen. 24 Count

Midol Complete Menstrual Pain Relief Caplets w/ Acetaminophen. 24 Count

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94%
4
Midol Complete Menstrual Pain Relief Gelcaps With Acetaminophen for Menstrual Symptom, PMS Relief, and Period Cramp Relief - 24 Count

Midol Complete Menstrual Pain Relief Gelcaps With Acetaminophen for Menstrual Symptom, PMS Relief, and Period Cramp Relief - 24 Co

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94%
5
Boiron Arnica Montana 30C, Homeopathic Medicine for Muscle Pain, Stiffness, Swelling From Injuries, Bruises, 80 Pellets

Boiron Arnica Montana 30C, Homeopathic Medicine for Muscle Pain, Stiffness, Swelling From Injuries, Bruises, 80 Pellets

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88%
6
Boiron Arnica Montana 200ck, 80 Pellets

Boiron Arnica Montana 200ck, 80 Pellets

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86%
7
Preparation H Hemorrhoid Symptom Treatment Cooling Gel (0.9 Ounce), Fast Discomfort Relief with Vitamin E and Aloe, Tube

Preparation H Hemorrhoid Symptom Treatment Cooling Gel (0.9 Ounce), Fast Discomfort Relief with Vitamin E and Aloe, Tube

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82%
8
EQ JR BBGUM MELT 24

EQ JR BBGUM MELT 24

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40%
9
Pfizer Tucks Hemorrhoidal Ointment, 1 oz

Pfizer Tucks Hemorrhoidal Ointment, 1 oz

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0%
10
Headon: Headache Extra Strength Pain Reliever, 0.20 oz

Headon: Headache Extra Strength Pain Reliever, 0.20 oz

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0%

1. Mentholatum Original Chest Rub Ointment, Jar, 1oz

Mentholatum Original Chest Rub Ointment, Jar, 1oz
94%

Our Score

Since 1889, Mentholatum ® Original Chest Rub Ointment has been trusted by families for generations to bring soothing, comforting relief for minor aches, pains and discomforts. Formulated with a gentle aroma, Mentholatum ® Original ointment helps relieve chest aches associated with colds. Its aromatic vapors are soothing and cooling to the nasal passages. Mentholatum ® Original chest rub provides temporary relief to minor aches and pains of muscles and joints, any time of year. Made with 100% natural active ingredients, this soothing chest rub contains camphor and menthol to create aromatic scent vapors that help you feel better. Apply this soothing chest rub ointment to the chest, neck and back, or achy muscles and joints, and feel the relief. Children under 2: Ask a doctor.

100% Natural Active Ingredients: Vapor Rub Ointment is formulated with natural camphor and menthol to provide soothing, comforting relief for aches and pains associated with colds and cough Aromatic Vapors: Aromatic vapors soothe nasal passages for long-lasting comfort Fast Acting Pain Relief: The ointment's deep-penetrating formula ensures fast-acting, long-lasting relief, so you can breathe easier and feel better Safe and Effective: Mentholatum topical chest rubs are safe to use for adults and children 2 years and up; Help your kids feel better faster, giving you peace of mind Trusted Brand: Trusted for generations since 1889, Mentholatum has been a trusted name in family care, providing comfort when you need it most Adults and children 2 years and over: apply to affected area not more than 3 to 4 times daily. Children under 2 years: ask a doctor.

2. Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, 16 ct

Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, 16 ct
94%

Our Score

Midol Complete Menstrual Pain Relief Caplets with Acetaminophen for Menstrual Symptom Relief provide up to six hours of PMS and period cramps relief to help you feel better and stay active during and right before your menstrual cycle. Available in convenient and easy to take caplets, Midol Complete contains acetaminophen with caffeine and pyrilamine maleate, combining a pain reliever, diuretic and antihistamine to effectively relieve period cramps, headache, backache, muscle ache, bloating, fatigue and water weight gain. These powerful menstrual cramp relief caplets are recommended for adults and children 12 years and older. Use as directed. Take two caplets with water and repeat every six hours as needed, but don't take more than six caplets a day.

Midol Complete, Menstrual Period Symptoms Relief, Caplets, 16 Count: One box of 16 count Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, Caffeine and Pyrilamine Maleate for Menstrual Symptom Relief Contains acetaminophen for effective period pain relief while also providing backache, muscle ache and headache relief Includes caffeine and pyrilamine maleate to relieve fatigue, bloating and water weight gain Available in easy to take caplet form for effective period pain and PMS relief you can take with you everywhere you go Recommended for adults and children 12 years and older Take two caplets with water and repeat every six hours as needed, but don't take more than six caplets a day

3. Midol Complete Menstrual Pain Relief Caplets w/ Acetaminophen. 24 Count

Midol Complete Menstrual Pain Relief Caplets w/ Acetaminophen. 24 Count
94%

Our Score

Midol Complete Menstrual Pain Relief Caplets with Acetaminophen for Menstrual Symptom Relief provide up to six hours of PMS and period cramps relief to help you feel better and stay active during and right before your menstrual cycle. Available in convenient and easy to take caplets, Midol Complete contains acetaminophen with caffeine and pyrilamine maleate, combining a pain reliever, diuretic and antihistamine to effectively relieve period cramps, headache, backache, muscle ache, bloating, fatigue and water weight gain. These powerful menstrual cramp relief caplets are recommended for adults and children 12 years and older. Use as directed. Take two caplets with water and repeat every six hours as needed, but don't take more than six caplets a day.

One box of 24 count Midol Complete Menstrual Pain Relief Caplets with Acetaminophen, Caffeine and Pyrilamine Maleate for Menstrual Symptom Relief Contains acetaminophen for effective period pain relief while also providing backache, muscle ache and headache relief Includes caffeine and pyrilamine maleate to relieve fatigue, bloating and water weight gain Available in easy to take caplet form for effective period pain and PMS relief you can take with you everywhere you go Recommended for adults and children 12 years and older Take two caplets with water and repeat every six hours as needed, but don't take more than six caplets a day

4. Midol Complete Menstrual Pain Relief Gelcaps With Acetaminophen for Menstrual Symptom, PMS Relief, and Period Cramp Relief - 24 Count

Midol Complete Menstrual Pain Relief Gelcaps With Acetaminophen for Menstrual Symptom, PMS Relief, and Period Cramp Relief - 24 Count
94%

Our Score

Midol Complete Menstrual Pain Relief Gelcaps with Acetaminophen for Menstrual Symptom Relief help you feel your best during and right before your period, delivering effective PMS and menstrual cramp relief in easy to take gelcap form. Midol Complete features a powerful formula with a pain reliever, diuretic and antihistamine. Combining acetaminophen with caffeine and pyrilamine maleate, these gelcaps provide muscle pain relief and bloating relief, as well as relief from period cramps, headache, back pain, water weight gain and fatigue. This period pain reliever is recommended for adults and children 12 years and older. Use as directed. Take two gelcaps with water and repeat every six hours as needed without exceeding six gelcaps a day.

One box of 24 count Midol Complete Menstrual Pain Relief Gelcaps with Acetaminophen, Caffeine and Pyrilamine Maleate for Menstrual Symptom Relief Contains acetaminophen for period cramps relief, as well as muscle ache, back pain and headache relief Includes caffeine and pyrilamine maleate Gelcaps are easy to take, offering period pain and PMS relief for up to six hours Recommended for adults and children 12 years and older Take two gelcaps with water and repeat every six hours as needed without exceeding six gelcaps per day

5. Boiron Arnica Montana 30C, Homeopathic Medicine for Muscle Pain, Stiffness, Swelling From Injuries, Bruises, 80 Pellets

Boiron Arnica Montana 30C, Homeopathic Medicine for Muscle Pain, Stiffness, Swelling From Injuries, Bruises, 80 Pellets
88%

Our Score

Boiron Arnica montana pellets provide targeted relief for minor muscle pain, stiffness, swelling from injuries, and bruises.* A homeopathic medicine, Arnica is non-drowsy and has no known interactions with other medications, herbs, or supplements. The meltaway pellets are easy to take without water, making them convenient to use anywhere. *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.

Formulated with Arnica montana, a single active ingredient for targeted relief. Can be used with Boiron Arnicare® Gel, Cream, or Ointment for complementary relief. No known drug interactions. Non-drowsy & NSAID-free. Easy to take — no food or water needed. Recommended for adults and children. No artificial sweeteners, flavors, colors, or preservatives. Available over the counter in an easy dispensing tube of approximately 80 oral pellets. HSA & FSA eligible. Made by Boiron, the Arnica expert, whose pain relief line also includes topical gel, cream and ointment, oral meltaway tablets, bruise relief, and arthritis pain formulas.

6. Boiron Arnica Montana 200ck, 80 Pellets

Boiron Arnica Montana 200ck, 80 Pellets
86%

Our Score

Homeopathic Medicine Main Indication: Muscle Pain and Stiffness, Swelling from Injuries, Discoloration from Bruising Common Name: Leopard's Bane Use For symptoms listed below. *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated. *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.

Boiron Arnica montana 200CK Pellets, 80 Ct

7. Preparation H Hemorrhoid Symptom Treatment Cooling Gel (0.9 Ounce), Fast Discomfort Relief with Vitamin E and Aloe, Tube

Preparation H Hemorrhoid Symptom Treatment Cooling Gel (0.9 Ounce), Fast Discomfort Relief with Vitamin E and Aloe, Tube
82%

Our Score

When hemorrhoids flare up and disrupt your day, trust Preparation H Cooling Gel for fast, cooling relief. There are several uncomfortable symptoms of hemorrhoids including painful burning, anus itching and swelling. Preparation H Cooling Gel contains vitamin E and aloe for soothing, cool relief of external hemorrhoid symptoms. Plus, Preparation H gel is clear, non-greasy, non-staining and has no unpleasant odor. At the first sign of hemorrhoid discomfort, treat with Preparation H Cooling Gel. In fact, treating signs of hemorrhoid symptoms early can help prevent further irritation. While treatment with hemorrhoid gel, cream or ointment may not provide a cure for hemorrhoids, it can help manage the symptoms. Trust the #1 doctor recommended hemorrhoid brand (2), Preparation H, to relieve your hemorrhoid pain, itching and burning. And for more comfortable relief, cleanse and soothe with Preparation H Medicated Wipes before applying Preparation H Cooling Gel. NET WT 1.8 OZ (51g) (1) IRI retail sales data supports that Preparation H is the #1 selling hemorrhoid brand in the U.S. (52 weeks ending August 13, 2017). (2) Provoice survey dated from May 2015-August 2017 supports Preparation H is the #1 doctor recommend brand.

Preparation H Cooling Gel Hemorrhoid Treatment, 0.9 0z tube, one tube per box Trust Preparation H Cooling Gel for fast, cooling relief when hemorrhoid flare ups disrupt your day Symptoms of hemorrhoids can include painful burning, anus itching and swelling Contains vitamin E and aloe for soothing, cool relief of external hemorrhoid symptoms Preparation H gel is clear, non-greasy, non-staining and has no unpleasant odor Treat with Preparation H Hemorrhoidal Cooling Gel at the first signs of hemorrhoid discomfort Treating signs of hemorrhoid symptoms early can help prevent further irritation Hemorrhoid gel, cream or ointments may not provide a cure for hemorrhoids, but can help manage the symptoms and get you back to doing what you love For even more comfortable relief, cleanse and soothe with Preparation H Medicated Wipes before applying Preparation H Cooling Gel Preparation H is the #1 doctor recommended hemorrhoid brand (2) NET WT 1.8 OZ (51g)

8. EQ JR BBGUM MELT 24

EQ JR BBGUM MELT 24
40%

Our Score

 

 

9. Pfizer Tucks Hemorrhoidal Ointment, 1 oz

Pfizer Tucks Hemorrhoidal Ointment, 1 oz
0%

Our Score

Hemorrhoidal Ointment 1 oz (28.3 g) Formerly Anusol. Relieves burning, itching and discomfort. Maximum strength pain reliever. Soothes and protects irritated tissue. Made in Canada. Temporarily relieves these local symptoms associated with hemorrhoids and other anorectal disorders: pain; soreness; burning; itching. Temporarily forms a protective coating over inflamed tissues to help prevent drying of tissues. Adults: Apply externally to the affected area up to 5 times daily; When practical, clean the affected area with mild soap an warm water and rinse thoroughly; Gently dry by patting or blotting with toilet tissue or a soft cloth before applying; To Use Dispensing Cap: Attach it to tube, lubricate well, then gently insert part way into anus; Squeeze tube to deliver medication; Thoroughly cleanse dispensing cap after use. Children Under 12 Years of Age: Ask a doctor. Store at 20 to 25 degrees C (68 to 77 degrees F). For external use only. When using this product do not use more than directed unless told to do so by a doctor; do not put into the rectum by using fingers or any mechanical device or applicator. Stop use and ask a doctor if allergic reaction occurs; rectal bleeding occurs; redness, irritation, swelling, pain, or other symptoms begin or increase; condition worsens of does not improve within 7 days. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Quality sealed for your protection. Do not use is seal or tube is broken or punctured. 1 oz (28.3 g) Morris Plains, NJ 07950 800-223-0182 2005 Pfizer

Hemorrhoidal Ointment Formerly Anusol. Relieves burning, itching and discomfort. Maximum strength pain reliever. Soothes and protects irritated tissue. Made in Canada.

10. Headon: Headache Extra Strength Pain Reliever, 0.20 oz

Headon: Headache Extra Strength Pain Reliever, 0.20 oz
0%

Our Score

Headon: Headache Extra Strength Pain Reliever, 0.20 oz

Headon: Headache Extra Strength Pain Reliever, 0.20 oz


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